ICPHSP2003 

                                                                                                         

“Effects of Different Weight-Loss Percentages on Moderate to Severe Obstructive Sleep Apnea Syndrome”                                  Click here to download Pdf file.

 

 

 Authors:    Christopher Papandreou1, Christos M. Hatzis2, Georgios A. Fragkiadakis1

 

 

Affiliation:  1Department of Nutrition & Dietetics, Technological Education Institute of Crete, Sitia, Greece

                      2Department of Social Medicine, Preventive Medicine and Nutrition Clinic, Medical School, University of Crete, Heraklion, Crete,  Greece

 

Abstract:

Obese individuals are encouraged to lose 5-10% of their weight to improve obstructive sleep apnoea syndrome (OSAS) but data supporting this recommendation are limited, particularly in moderate to severe cases. Whether a 5-10% weight loss range is more beneficial in moderate and/or severe OSAS compared with less weight loss (<5%) is the main focus of this study.

A series of consecutive patients, who were diagnosed with OSAS by overnight attended polysomnography at the Sleep Disorders Unit, Dept of Thoracic Medicine, Medical School, University of Crete (Heraklion, Greece), during a 1-yr period (November 2008 to October 2009) were evaluated. Forty obese patients with moderate to severe OSAS were categorized into three categories according to their weight change (0-4.9%, 5-9.9% and >10%), six months after the implementation of a dietary (Mediterranean diet or prudent diet) and physical activity program. The change in apnoea-hypopnoea index (AHI), apnoea-hypopnoea index during rapid eye movement (AHI/REM) sleep, arousal index, oxygen saturation and desaturation were the objective outcome variables.

The highest weight loss category showed a greater improvement in AHI/REM and lowest oxygen saturation compared to the lowest (P<0.05). The latter OSAS parameter also improved significantly more in the highest category than in the intermediate (P<0.05). The comparison between the lowest and intermediate weight-loss category did not reveal any significant differences concerning changes in OSAS severity indices (P>0.05).

Our results showed that a >10% weight-loss was effective in improving OSAS severity indices compared to the other weight loss categories. A weight-loss ranging from 5 to 10% did not lead to a substantially greater improvement in OSAS parameters compared to the lowest weight-loss category (<5%).

 

Keywords:

Weight loss; Diet; OSAS; AHI/REM; Oxygen saturation

 

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